Article
Diabetes-related mortality in adults with cystic fibrosis. Role of genotype and sex.
American journal of respiratory and critical care medicine - 15 Jan 2015
Lewis Connor, Blackman Scott M, Nelson Amanda, Oberdorfer Ewa, Wells Daniel, Dunitz Jordan, Thomas William, Moran Antoinette
Abstract excerpt
RATIONALE: Diabetes is associated with increased mortality in cystic fibrosis. Aggressive screening and early institution of insulin treatment significantly reduced this risk over the period of 1992-2008. OBJECTIVES: To determine if progressive improvement in cystic fibrosis-related diabetes (CFRD) mortality has continued since 2008, and examine associations with CFTR genotypes linked to pancreatic insufficiency...
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