Reproducibility of native myocardial T1 mapping in the assessment of Fabry disease and its role in early detection of cardiac involvement by cardiovascular magnetic resonance.

doi:10.1186/s12968-014-0099-4

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Article

Reproducibility of native myocardial T1 mapping in the assessment of Fabry disease and its role in early detection of cardiac involvement by cardiovascular magnetic resonance.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance - 5 Dec 2014

Pica Silvia, Sado Daniel M, Maestrini Viviana, Fontana Marianna, White Steven K, Treibel Thomas, Captur Gabriella, Anderson Sarah, Piechnik Stefan K, Robson Matthew D, Lachmann Robin H, Murphy Elaine, Mehta Atul, Hughes Derralyn, Kellman Peter, Elliott Perry M, Herrey Anna S, Moon James C

Abstract excerpt

BACKGROUND: Cardiovascular magnetic resonance (CMR) derived native myocardial T1 is decreased in patients with Fabry disease even before left ventricular hypertrophy (LVH) occurs and may be the first non-invasive measure of myocyte sphingolipid storage. The relationship of native T1 lowering prior to hypertrophy and other candidate early phenotype markers are unknown. Furthermore, the reproducibility of T1...

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Identifiers

PMID: 25475749
DOI: 10.1186/s12968-014-0099-4
PMCID: PMC4256727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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