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Article

Identification of Biomarkers for PKD1 Using Urinary Exosomes.

Journal of the American Society of Nephrology : JASN - 1 Jul 2015

Hogan Marie C, Bakeberg Jason L, Gainullin Vladimir G, Irazabal Maria V, Harmon Amber J, Lieske John C, Charlesworth M Cristine, Johnson Kenneth L, Madden Benjamin J, Zenka Roman M, McCormick Daniel J, Sundsbak Jamie L, Heyer Christina M, Torres Vicente E, Harris Peter C, Ward Christopher J

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of ESRD. Affected individuals inherit a defective copy of either PKD1 or PKD2, which encode polycystin-1 (PC1) or polycystin-2 (PC2), respectively. PC1 and PC2 are secreted on urinary exosome-like vesicles (ELVs) (100-nm diame...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25475747
DOI: 10.1681/ASN.2014040354
PMCID: PMC4483583

Genes

PKD1
PKD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25475747-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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