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Lessons and implications from association studies and post-GWAS analyses of cervical cancer.

Trends in genetics : TIG - 1 Jan 2015

Chen Dan, Gyllensten Ulf

Abstract excerpt

Cervical cancer has a heritable genetic component. A large number of genetic associations with cervical cancer have been reported in hypothesis-driven candidate gene studies, but many of these results are either inconsistent or have failed to be independently replicated. Genome-wide association studies (GWAS) have identified additional susceptibility loci previously not implicated in cervical cancer development,...

Topics

Animals
Female
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Uterine Cervical Neoplasms

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 25467628
DOI: 10.1016/j.tig.2014.10.005

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