Article
Bone marrows from neuroblastoma patients: an excellent source for tumor genome analyses.
Molecular oncology - 1 Mar 2015
Abbasi M Reza, Rifatbegovic Fikret, Brunner Clemens, Ladenstein Ruth, Ambros Inge M, Ambros Peter F
Abstract excerpt
Neuroblastoma is the most common extra-cranial solid tumor in childhood. Presence of disseminated tumor cells (DTCs) in the bone marrow (BM) at diagnosis and at relapse is a common event in stage M neuroblastomas. Although the clinical heterogeneity of disseminated neuroblastomas is frequently associated with genomic diversity, so far, only little information exists about the genomic status of DTCs. This lack of...
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