Article
Cytogenetic and clinical marks for defining high-risk myeloma in the context of bortezomib treatment.
Experimental hematology - 1 Mar 2015
An Gang, Acharya Chirag, Deng Shuhui, Yi Shuhua, Xu Yan, Qin Xiaoqi, Sui Weiwei, Li Zengjun, Shi Lihui, Zang Meirong, Feng Xiaoyan, Hao Mu, Zou Dehui, Zhao Yaozhong, Qi Junyuan, Cheng Tao, Ru Kun, Wang Jianxiang, Tai Yu-Tzu, Qiu Lugui
Abstract excerpt
Multiple myeloma (MM) is a heterogeneous disease, and the benefit from bortezomib treatment is not uniform among all patients subgroups. Currently, little information is available to predict patients response to bortezomib treatment. In this study, we aimed to identify patients benefiting minimally from bortezomib as part of first-line therapy and to define high-risk MM in the context of bortezomib treatment. We...
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