New insights into schizophrenia disease genes interactome in the human brain: emerging targets and therapeutic implications in the postgenomics era.

Abstract excerpt

Schizophrenia, a complex neurological disorder, is comprised of interactions between multiple genetic and environmental factors wherein each of the factors individually exhibits a small effect. In this regard a network-based strategy is best suited to capture the combined effect of multiple genes with their definite pattern of interactions. Given that schizophrenia affects multiple regions of the brain, we...

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