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Article

Nuclear import factor transportin and arginine methyltransferase 1 modify FUS neurotoxicity in Drosophila.

Neurobiology of disease - 1 Feb 2015

Jäckel Sandra, Summerer Anna K, Thömmes Catherine M, Pan Xia, Voigt Aaron, Schulz Jörg B, Rasse Tobias M, Dormann Dorothee, Haass Christian, Kahle Philipp J

Abstract excerpt

Inclusions containing Fused in Sarcoma (FUS) are found in familial and sporadic cases of the incurable progressive motor neuron disease amyotrophic lateral sclerosis and in a common form of dementia, frontotemporal dementia. Most disease-associated mutations are located in the C-terminal proline-...

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Source

Identifiers

PMID: 25447237
DOI: 10.1016/j.nbd.2014.11.003

Genes

FUS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25447237-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Nuclear import factor transportin and arginine methyltransferase 1 modify FUS neurotoxicity in Drosophila.PMID 25447237Read ↗

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