Article
[Genetic and epigenetic mechanisms in obesity].
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - 1 Feb 2015
Hinney A, Herrfurth N, Schonnop L, Volckmar A-L
Abstract excerpt
Obesity is a relevant medical problem. Around 60 % of German adults are overweight, 20 % are obese. The hereditary contribution to the variance of body weight is high. Nevertheless, molecular genetic studies have as yet explained only a small part of the inter-individual variability in the body mass index (BMI). Monogenic forms of obesity, in which loss of a single gene product leads to extreme obesity, are very...
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