Article
FGF23 gene variation and its association with phosphate homeostasis and bone mineral density in Finnish children and adolescents.
Bone - 1 Feb 2015
Pekkinen Minna, Laine Christine M, Mäkitie Riikka, Leinonen Eira, Lamberg-Allardt Christel, Viljakainen Heli, Mäkitie Outi
Abstract excerpt
Fibroblast growth factor 23 (FGF23), a bone-derived hormone, participates in the hormonal bone-parathyroid-kidney axis, which is modulated by PTH, 1,25-dihydroxyvitamin D, plasma phosphate (Pi), and diet. Inappropriately high serum FGF23, seen in certain genetic and acquired disorders, results in...
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