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Article

Assessment of HaloPlex amplification for sequence capture and massively parallel sequencing of arrhythmogenic right ventricular cardiomyopathy-associated genes.

The Journal of molecular diagnostics : JMD - 1 Jan 2015

Gréen Anna, Gréen Henrik, Rehnberg Malin, Svensson Anneli, Gunnarsson Cecilia, Jonasson Jon

Abstract excerpt

The genetic basis of arrhythmogenic right ventricular cardiomyopathy (ARVC) is complex. Mutations in genes encoding components of the cardiac desmosomes have been implicated as being causally related to ARVC. Next-generation sequencing allows parallel sequencing and duplication/deletion analysis of many genes simultaneously, which is appropriate for screening of mutations in disorders with heterogeneous genetic...

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Share to Arrhythmogenic Right Ventricular Dysplasia
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25445213
DOI: 10.1016/j.jmoldx.2014.09.006

Genes

DSP
DSC2
DSG2
JUP
PKP2
DES
RYR2
TGFB3
TMEM43
TTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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