Article
Monitoring liver macrophages using nanobodies targeting Vsig4: concanavalin A induced acute hepatitis as paradigm.
Immunobiology - 1 Feb 2015
Zheng Fang, Devoogdt Nick, Sparkes Amanda, Morias Yannick, Abels Chloé, Stijlemans Benoit, Lahoutte Tony, Muyldermans Serge, De Baetselier Patrick, Schoonooghe Steve, Beschin Alain, Raes Geert
Abstract excerpt
Kupffer cells (KCs) are liver resident macrophages which are important for tissue homeostasis and have been implicated in immunogenic, tolerogenic and pathogenic immune reactions depending on the insult. These cells and the biomarkers they express thus represent interesting in vivo sensors for mo...
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