Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ophthalmologic correlates of disease severity in children and adolescents with Wolfram syndrome.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus - 1 Oct 2014

Hoekel James, Chisholm Smith Ann, Al-Lozi Amal, Hershey Tamara, Tychsen Lawrence

Abstract excerpt

PURPOSE: To describe an ophthalmic phenotype in children at relatively early stages of Wolfram syndrome. METHODS: Quantitative ophthalmic testing of visual acuity, color vision, automated visual field sensitivity, optic nerve pallor and cupping, and retinal nerve fiber layer (RNFL) thickness assessed by optical coherence tomography (OCT) was performed in 18 subjects 5-25 years of age. Subjects were also examined...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Color Vision
Share to Eye Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nerve Fibers

Share to Nystagmus, Pathologic

Share to Optic Nerve Diseases

Share to Retinal Ganglion Cells

Share to Vision Disorders

Share to Wolfram Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 25439303
DOI: 10.1016/j.jaapos.2014.07.162
PMCID: PMC4476046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ophthalmologic correlates of disease severity in children and adolescents with Wolfram syndrome.PMID 25439303Read ↗

Optic Atrophy in Wolfram Syndrome Type 1: A Retrospective Analysis of Visual Outcomes and Biomarker Correlates.Semantic proximity Read ↗

Spectrum of Ophthalmic Disorders in Prader-Willi Syndrome: Implications for Early Screening and Multidisciplinary ManagementSemantic proximity Read ↗

Ocular Manifestations in Patients with Werner Syndrome.Semantic proximity Read ↗

Kjellin syndrome: long-term neuro-ophthalmologic follow-up and novel mutations in the SPG11 gene.Semantic proximity Read ↗

Delineating Wolfram-like syndrome: A systematic review and discussion of the WFS1-associated disease spectrum.Semantic proximity Read ↗

[Wolfram-like syndrome: a case report].Semantic proximity Read ↗

Wolfram Syndrome: a rare optic neuropathy in youth with type 1 diabetes.Semantic proximity Read ↗

WFS1 in Optic Neuropathies: Mutation Findings in Nonsyndromic Optic Atrophy and Assessment of Clinical Severity.Semantic proximity Read ↗

WFS1-Associated Optic Neuropathy: Genotype-Phenotype Correlations and Disease ProgressionSemantic proximity Read ↗

The phenotypic spectrum of syndromic optic atrophy associated with variants in WFS1: with reclassification of p.Val606Gly as a likely benign variant.Semantic proximity Read ↗

A mutant wfs1 zebrafish model of Wolfram syndrome manifesting visual dysfunction and developmental delay.Semantic proximity Read ↗

Characteristics of autosomal dominant WFS1-associated optic neuropathy and its comparability to OPA1-associated autosomal dominant optic atrophy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.