Article
CD100 up-regulation induced by interferon-α on B cells is related to hepatitis C virus infection.
PloS one - 1 Jan 2014
He Yu, Guo Yonghong, Zhou Yun, Zhang Ying, Fan Chao, Ji Guangxi, Wang Yu, Ma Zhiyuan, Lian Jianqi, Hao Chunqiu, Yao Zhi Q, Jia Zhansheng
Abstract excerpt
OBJECTIVES: CD100, also known as Sema4D, is a member of the semaphorin family and has important regulatory functions that promote immune cell activation and responses. The role of CD100 expression on B cells in immune regulation during chronic hepatitis C virus (HCV) infection remains unclear. MATERIALS AND METHODS: We longitudinally investigated the altered expression of CD100, its receptor CD72, and other...
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