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Article

Increased alcohol consumption as a cause of alcoholism, without similar evidence for depression: a Mendelian randomization study.

International journal of epidemiology - 1 Apr 2015

Wium-Andersen Marie Kim, Ørsted David Dynnes, Tolstrup Janne Schurmann, Nordestgaard Børge Grønne

Abstract excerpt

BACKGROUND: Increased alcohol consumption has been associated with depression and alcoholism, but whether these associations are causal remains unclear. We tested whether alcohol consumption is causally associated with depression and alcoholism. METHODS: We included 78,154 men and women aged 20-100 years randomly selected in 1991-2010 from the general population of Copenhagen, Denmark, and genotyped 68,486...

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PMID: 25433705
DOI: 10.1093/ije/dyu220

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