Laser capture microdissection followed by next‐generation sequencing identifies disease‐related micro <scp>RNA</scp> s in psoriatic skin that reflect systemic micro <scp>RNA</scp> changes in psoriasis

Abstract excerpt

Psoriasis is a systemic disease with cutaneous manifestations. MicroRNAs (miRNAs) are small non-coding RNA molecules that are differentially expressed in psoriatic skin; however, only few cell- and region-specific miRNAs have been identified in psoriatic lesions. We used laser capture microdissection (LCM) and next-generation sequencing (NGS) to study the specific miRNA expression profiles in the epidermis (Epi)...

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