Arg972 insulin receptor substrate-1 polymorphism and risk and severity of rheumatoid arthritis.

doi:10.1111/1756-185X.12366

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Arg972 insulin receptor substrate-1 polymorphism and risk and severity of rheumatoid arthritis.

International journal of rheumatic diseases - 1 Feb 2016

Zhao Hongjun, Liu Shiqing, Long Mei, Peng Lijuan, Deng Hongxiang, You Yunhui

Abstract excerpt

AIM: To explore the association between the Arg(972) insulin receptor substrate (IRS)-1 polymorphism (rs1801278) and the risk and disease activity/severity of rheumatoid arthritis (RA). METHOD: We genotyped the Arg(972) IRS-1 polymorphism in 871 pairs of age-, sex-, body mass index-, residence area- and current smoking status-matched RA patients and controls. We assessed RA severity using the disease activity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Genetic Association Studies

Share to Heterozygote

Share to Homozygote

Share to Insulin Receptor Substrate Proteins

Share to Protective Factors

Share to Severity of Illness Index

Source

Open in PubMed

Identifiers

PMID: 25424426
DOI: 10.1111/1756-185X.12366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Arg972 insulin receptor substrate-1 polymorphism and risk and severity of rheumatoid arthritis.PMID 25424426Read ↗

Arg972 insulin receptor substrate-1 polymorphism and risk and severity of Alzheimer's disease.Semantic proximity Read ↗

Interleukin-1 receptor-associated kinase gene polymorphisms contribute to rheumatoid arthritis risk: A meta-analysis.Semantic proximity Read ↗

RORC2 Genetic Variants and Serum Levels in Patients with Rheumatoid Arthritis.Semantic proximity Read ↗

Susceptibility for and clinical manifestations of rheumatoid arthritis are associated with polymorphisms of the TNF-alpha, IL-1beta, and IL-1Ra genes.Semantic proximity Read ↗

Association of polymorphisms modulating low-density lipoprotein cholesterol with susceptibility, severity, and progression of rheumatoid arthritis.Semantic proximity Read ↗

Interleukin 1 receptor antagonist (IL1RN) gene variants predict radiographic severity of knee osteoarthritis and risk of incident disease.Semantic proximity Read ↗

Tumor necrosis factor receptor II gene polymorphism and severity of rheumatoid arthritis.Semantic proximity Read ↗

Relationship of polymorphisms of the Interleukin-1 gene cluster to occurrence and severity of rheumatoid arthritis.Semantic proximity Read ↗

Arg972 insulin receptor substrate-1 enhances tumor necrosis factor-α-induced apoptosis in osteoblasts.Semantic proximity Read ↗

beta2 Adrenoceptor gene single nucleotide polymorphisms are associated with rheumatoid arthritis in northern Sweden.Semantic proximity Read ↗

Association of +3179G/A insulin-like growth factor-1 receptor polymorphism and insulin-like growth factor-1 serum level with systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.