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Article

Multiple biopsies and detection of cervical cancer precursors at colposcopy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jan 2015

Wentzensen Nicolas, Walker Joan L, Gold Michael A, Smith Katie M, Zuna Rosemary E, Mathews Cara, Dunn S Terence, Zhang Roy, Moxley Katherine, Bishop Erin, Tenney Meaghan, Nugent Elizabeth, Graubard Barry I, Wacholder Sholom, Schiffman Mark

Abstract excerpt

PURPOSE: Women with abnormal cervical cancer screening results are referred to colposcopy and biopsy for diagnosis of cervical cancer precursors (high-grade squamous intraepithelial lesions [HSILs]). Colposcopy with a single biopsy can miss identification of HSILs. No systematic study has quantified the improved detection of HSIL by taking multiple lesion-directed biopsies. METHODS: The Biopsy Study was an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25422481
DOI: 10.1200/JCO.2014.55.9948
PMCID: PMC4268255

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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