Article
Single nucleotide differences (SNDs) continue to contaminate the dbSNP database with consequences for human genomics and health.
Human mutation - 1 Feb 2015
Arthur Jonathan W, Cheung Florence S G, Reichardt Juergen K V
Abstract excerpt
It has been established that up to 8.3% of the biallelic coding SNPs present in dbSNP are actually artefactual polymorphism-like errors, previously termed single nucleotide differences, or SNDs. In this study, a previous analysis of SNPs in dbSNP was extended and updated to examine how the incidence of SNDs has changed over an intervening five year period. The incidence of SNDs was found to be lower than in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.