Article
Whole genome sequencing reveals potential spread of Clostridium difficile between humans and farm animals in the Netherlands, 2002 to 2011.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 13 Nov 2014
Knetsch C W, Connor T R, Mutreja A, van Dorp S M, Sanders I M, Browne H P, Harris D, Lipman L, Keessen E C, Corver J, Kuijper E J, Lawley T D
Abstract excerpt
Farm animals are a potential reservoir for human Clostridium difficile infection (CDI), particularly PCR ribotype 078 which is frequently found in animals and humans. Here, whole genome single-nucleotide polymorphism (SNP) analysis was used to study the evolutionary relatedness of C. difficile 078 isolated from humans and animals on Dutch pig farms. All sequenced genomes were surveyed for potential antimicrobial...
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