Article
A microfluidic device and automatic counting system for the study of C. elegans reproductive aging.
Lab on a chip - 21 Jan 2015
Li Siran, Stone Howard A, Murphy Coleen T
Abstract excerpt
The nematode Caenorhabditis elegans (C. elegans) is an excellent model to study reproductive aging because of its short life span, its cessation of reproduction in mid-adulthood, and the strong conservation of pathways that regulate longevity. During its lifetime, a wild-type C. elegans hermaphrodite usually lays about 200-300 self-fertilized hatchable eggs, which mainly occurs in the first three to five days of...
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