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Article

An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging.

Scientific reports - 7 May 2015

Cornaglia Matteo, Mouchiroud Laurent, Marette Alexis, Narasimhan Shreya, Lehnert Thomas, Jovaisaite Virginija, Auwerx Johan, Gijs Martin A M

Abstract excerpt

Studies of the real-time dynamics of embryonic development require a gentle embryo handling method, the possibility of long-term live imaging during the complete embryogenesis, as well as of parallelization providing a population's statistics, while keeping single embryo resolution. We describe an automated approach that fully accomplishes these requirements for embryos of Caenorhabditis elegans, one of the most...

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PMID: 25950235
DOI: 10.1038/srep10192
PMCID: PMC4423638

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