Article
Weight loss during telaprevir-based triple therapy due to telaprevir-induced appetite loss.
Internal medicine (Tokyo, Japan) - 1 Jan 2014
Nomura Hideyuki, Miyagi Yuugou, Tanimoto Hironori, Kawano Akira, Yamashita Nobuyuki
Abstract excerpt
OBJECTIVE: The sustained virological response (SVR) rate has improved to >70% for patients with hepatitis C virus genotype 1 treated with the triple therapy of telaprevir (TVR), pegylated interferon (PEG-IFN)-α, and ribavirin (RBV). However, this therapy has various adverse effects, although there have been no reports of it decreasing body weight. METHODS: A total of 175 patients with chronic hepatitis C received...
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