Article
Telaprevir.
Prescrire international - 1 Apr 2012
Abstract excerpt
The standard treatment for genotype 1 chronic hepatitis C consists of the peginterferon alfa + ribavirin combination taken for 24 to 48 weeks. When added to this combination, boceprevir, an inhibitor of hepatitis C virus (HCV) NS3/4A serine protease, increases virological efficacy at a cost of generally acceptable adverse effects (mainly anaemia). However, more trials are needed to assess its impact on morbidity...
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