Article
Establishment of a New Ovarian Cancer Cell Line CA5171.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Jun 2015
Chiang Ying-Cheng, Cheng Wen-Fang, Chang Ming-Cheng, Lu Tzu-Pin, Kuo Kuan-Ting, Lin Hsiu-Ping, Hsieh Chang-Yao, Chen Chi-An
Abstract excerpt
A new cell line, CA5171, derived from a chemotherapy-naive, high-grade undifferentiated ovarian carcinoma was established and characterized. The CA5171 cells presented with cobblestone morphology and a doubling time of 24 hours. Gene mutation analysis showed that the cells belonged to the type II ovarian cancer pathway with mutations of PIK3CA, PTEN, and TP53. Single-nucleotide polymorphism array analysis showed...
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