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Article

Polymorphism of LRP5 gene and emphysema severity are associated with osteoporosis in Japanese patients with or at risk for COPD.

Respirology (Carlton, Vic.) - 1 Feb 2015

Chubachi Shotaro, Nakamura Hidetoshi, Sasaki Mamoru, Haraguchi Mizuha, Miyazaki Masaki, Takahashi Saeko, Tanaka Kyuto, Funatsu Yohei, Asano Koichiro, Betsuyaku Tomoko

Abstract excerpt

BACKGROUND AND OBJECTIVE: Osteoporosis is an important systemic comorbidity of chronic obstructive pulmonary disease (COPD). However, neither its mechanisms nor its risk factors have been fully elucidated. With regard to genetic factors, low-density lipoprotein receptor-related protein 5 (LRP5) A1330V is known to be associated with osteoporosis in the general population, but the influence of this polymorphism in...

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Source

Identifiers

PMID: 25392953
DOI: 10.1111/resp.12429

Genes

LRP5

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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