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Article

Cell surface markers of functional phenotypic corneal endothelial cells.

Investigative ophthalmology & visual science - 11 Nov 2014

Okumura Naoki, Hirano Hiroatsu, Numata Ryohei, Nakahara Makiko, Ueno Morio, Hamuro Junji, Kinoshita Shigeru, Koizumi Noriko

Abstract excerpt

PURPOSE: Cultured human corneal endothelial cells (HCECs) are anticipated to serve as an alternative to donor corneas for the treatment of corneal endothelial dysfunction. However, corneal endothelial cells (CECs) tend to exhibit fibroblastic transformation, thereby losing their functional phenotype when cultured. The purpose of this study was to investigate the usefulness of surface markers of CECs displaying...

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Identifiers

PMID: 25389199
DOI: 10.1167/iovs.14-14980

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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