Article
Dual effects of a targeted small-molecule inhibitor (cabozantinib) on immune-mediated killing of tumor cells and immune tumor microenvironment permissiveness when combined with a cancer vaccine.
Journal of translational medicine - 13 Nov 2014
Kwilas Anna R, Ardiani Andressa, Donahue Renee N, Aftab Dana T, Hodge James W
Abstract excerpt
BACKGROUND: Growing awareness of the complexity of carcinogenesis has made multimodal therapies for cancer increasingly compelling and relevant. In recent years, immunotherapy has gained acceptance as an active therapeutic approach to cancer treatment, even though cancer is widely considered an i...
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