Article
Role of telaprevir plasma levels for predicting response to antiviral therapy in patients with hepatitis C virus genotype 1 infection.
Scandinavian journal of gastroenterology - 1 Dec 2014
Farnik Harald, Ferreirós Nerea, Labocha Sandra, Geisslinger Gerd, Zeuzem Stefan, Sarrazin Christoph, Vermehren Johannes
Abstract excerpt
OBJECTIVE: Telaprevir (TVR)-based triple therapy has substantially improved cure rates of hepatitis C virus (HCV) genotype 1 infection but side effects are frequent and often severe. Therefore, response predictors are needed for early identification of patients not responding to TVR-based triple therapy. MATERIAL AND METHODS: Forty-five patients (mean age: 54 ± 13 years; male gender: 60%; treatment-experienced:...
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