Article
Telaprevir for previously treated chronic HCV infection.
The New England journal of medicine - 8 Apr 2010
McHutchison John G, Manns Michael P, Muir Andrew J, Terrault Norah A, Jacobson Ira M, Afdhal Nezam H, Heathcote E Jenny, Zeuzem Stefan, Reesink Hendrik W, Garg Jyotsna, Bsharat Mohammad, George Shelley, Kauffman Robert S, Adda Nathalie, Di Bisceglie Adrian M
Abstract excerpt
BACKGROUND: Patients with genotype 1 hepatitis C virus (HCV) who do not have a sustained response to therapy with peginterferon alfa and ribavirin have a low likelihood of success with retreatment. METHODS: We randomly assigned patients with HCV genotype 1 who had not had a sustained virologic response after peginterferon alfa-ribavirin therapy to one of four treatment groups: 115 patients to the T12PR24 group,...
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