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Article

Telomere length and the risk of atrial fibrillation: insights into the role of biological versus chronological aging.

Circulation. Arrhythmia and electrophysiology - 1 Dec 2014

Roberts Jason D, Dewland Thomas A, Longoria James, Fitzpatrick Annette L, Ziv Elad, Hu Donglei, Lin Jue, Glidden David V, Psaty Bruce M, Burchard Esteban G, Blackburn Elizabeth H, Olgin Jeffrey E, Heckbert Susan R, Marcus Gregory M

Abstract excerpt

BACKGROUND: Advanced age is the most important risk factor for atrial fibrillation (AF); however, the mechanism remains unknown. Telomeres, regions of DNA that shorten with cell division, are considered reliable markers of biological aging. We sought to examine the association between leukocyte telomere length (LTL) and incident AF in a large population-based cohort using direct LTL measurements and genetic data....

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Source

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Identifiers

PMID: 25381796
DOI: 10.1161/CIRCEP.114.001781
PMCID: PMC4294941

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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