Article
Closing the genotype-phenotype gap: emerging technologies for evolutionary genetics in ecological model vertebrate systems.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 2015
Kratochwil Claudius F, Meyer Axel
Abstract excerpt
The analysis of genetic and epigenetic mechanisms of the genotype-phenotypic connection has, so far, only been possible in a handful of genetic model systems. Recent technological advances, including next-generation sequencing methods such as RNA-seq, ChIP-seq and RAD-seq, and genome-editing approaches including CRISPR-Cas, now permit to address these fundamental questions of biology also in organisms that have...
Topics
- Animals
- Biological Evolution
- Cichlids
- Genotype
- Phenotype
- Vertebrates
