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Article

The CYP7A1 gene rs3808607 variant is associated with susceptibility of tuberculosis in Moroccan population.

The Pan African medical journal - 1 Jan 2014

Qrafli Mounia, Amar Youssef, Bourkadi Jamaleddine, Ben Amor Jouda, Iraki Ghali, Bakri Youssef, Amzazi Saaîd, Lahlou Ouafae, Seghrouchni Fouad, El Aouad Rajae, Sadki Khalid

Abstract excerpt

INTRODUCTION: Despite the medical progress in treatment. Tuberculosis (TB) continues to be a serious global health problem. A genome-wide linkage study identified a major susceptibility locus on chromosomal region 8q12-q13 in Moroccan TB patients. The CYP7A1 gene is located in this region and codes for cholesterol 7a-hydroxylase, an enzyme involved in cholesterol catabolism. METHODS: We selected three SNPs...

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Identifiers

PMID: 25360185
DOI: 10.11604/pamj.2014.18.1.3397
PMCID: PMC4212432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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