Article
Molecular evolutionary analysis of type-1 human astroviruses identifies putative sites under selection pressure on the capsid protein.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2018
De Grazia Simona, Lanave Gianvito, Bonura Floriana, Urone Noemi, Cappa Vincenzo, Li Muli Sara, Pepe Arcangelo, Gellért Akos, Banyai Krisztian, Martella Vito, Giammanco Giovanni M
Abstract excerpt
Human astroviruses (HAstV) are important enteric pathogens that can be classified into eight sero/genotypes (HAstV-1 to -8). Although the various HAstV types show global spread, type-1 strains tend to be predominant. Molecular analysis of the genomic region encoding the capsid protein (ORF2) has revealed discrete sequence variation, with different lineages within each HAstV type and at least three major lineages...
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