Article
KCNK18 (TRESK) genetic variants in Italian patients with migraine.
Headache - 1 Oct 2014
Rainero Innocenzo, Rubino Elisa, Gallone Salvatore, Zavarise Paola, Carli Daniela, Boschi Silvia, Fenoglio Pierpaola, Savi Lidia, Gentile Salvatore, Benna Paolo, Pinessi Lorenzo, Dalla Volta Giorgio
Abstract excerpt
OBJECTIVES: To evaluate the prevalence of KCNK18 gene mutations in a dataset of Italian migraineurs, with and without aura, and in healthy controls, and to investigate in silico the functional effects of the mutations. BACKGROUND: A role for the KCNK18 gene encoding for TRESK, a member of the family of potassium channel, has been recently suggested in migraine with aura. METHODS: We sequenced the KCNK18 gene in...
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