Article
Detection of clonal evolution in hematopoietic malignancies by combining comparative genomic hybridization and single nucleotide polymorphism arrays.
Clinical chemistry - 1 Dec 2014
Hartmann Luise, Stephenson Christine F, Verkamp Stephanie R, Johnson Krystal R, Burnworth Bettina, Hammock Kelle, Brodersen Lisa Eidenschink, de Baca Monica E, Wells Denise A, Loken Michael R, Zehentner Barbara K
Abstract excerpt
BACKGROUND: Array comparative genomic hybridization (aCGH) has become a powerful tool for analyzing hematopoietic neoplasms and identifying genome-wide copy number changes in a single assay. aCGH also has superior resolution compared with fluorescence in situ hybridization (FISH) or conventional...
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