Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of the Internal Genes of Influenza A (H7N9) Virus Contributing to High Pathogenicity in Mice

16 Oct 2014

Abstract excerpt

UNLABELLED: The recently identified H7N9 influenza A virus has caused severe economic losses and worldwide public concern. Genetic analysis indicates that its six internal genes all originated from H9N2 viruses. However, the H7N9 virus is more highly pathogenic in humans than H9N2, which suggests that the internal genes of H7N9 have mutated. To analyze which H7N9 virus internal genes contribute to its high...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Influenza Virus Research Studies
Share to Poxvirus research and outbreaks
Share to Respiratory viral infections research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25320305
DOI: 10.1128/jvi.02390-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of the Internal Genes of Influenza A (H7N9) Virus Contributing to High Pathogenicity in MicePMID 25320305Read ↗

Origin and Characteristics of Internal Genes Affect Infectivity of the Novel Avian-Origin Influenza A (H7N9) VirusSemantic proximity Read ↗

Evolution and Adaptation of the Avian H7N9 Virus into the Human HostSemantic proximity Read ↗

The Origin of Internal Genes Contributes to the Replication and Transmission Fitness of H7N9 Avian Influenza VirusSemantic proximity Read ↗

The origin of internal genes contributes to the replication and transmission fitness of H7N9 avian influenza virusSemantic proximity Read ↗

Amino acid mutations PB1-V719M and PA-N444D combined with PB2-627K contribute to the pathogenicity of H7N9 in mice.Semantic proximity Read ↗

Enhanced pathogenicity and transmissibility of H9N2 avian influenza virus in mammals by hemagglutinin mutations combined with PB2-627K.Semantic proximity Read ↗

Rapid Reassortment of Internal Genes in Avian Influenza A(H7N9) VirusSemantic proximity Read ↗

Altered virulence of Highly Pathogenic Avian Influenza (HPAI) H5N8 reassortant viruses in mammalian modelsSemantic proximity Read ↗

The Effects of Genetic Variation on H7N9 Avian Influenza Virus Pathogenicity.Semantic proximity Read ↗

Avian influenza virus hemagglutinins H2, H4, H8, and H14 support a highly pathogenic phenotypeSemantic proximity Read ↗

Virulence and transmission characteristics of clade 2.3.4.4b H5N6 subtype avian influenza viruses possessing different internal gene constellations.Semantic proximity Read ↗

Prevailing PA Mutation K356R in Avian Influenza H9N2 Virus Increases Mammalian Replication and PathogenicitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.