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Article

The Host Response: Toll-Like Receptor Expression in Periprosthetic Tissues as a Biomarker for Deep Joint Infection

15 Oct 2014

Abstract excerpt

BACKGROUND: Toll-like receptors (TLRs) 1 and 6 are consistent molecular indicators of the host inflammatory response against bacterial infection. Our aims were to determine whether TLR elevation could be detected in infected periprosthetic tissues and to assess the utility of these biomarkers as tests for detecting a periprosthetic joint infection. METHODS: Fifty-nine patients undergoing revision total joint...

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PMID: 25320195
DOI: 10.2106/jbjs.m.01295

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