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The Alpha Defensin-1 Biomarker Assay can be Used to Evaluate the Potentially Infected Total Joint Arthroplasty

25 Sept 2014

Abstract excerpt

BACKGROUND: Diagnosing a periprosthetic joint infection (PJI) requires a complex approach using various laboratory and clinical criteria. A novel approach to diagnosing these infections uses synovial fluid biomarkers. Alpha defensin-1 (AD-1) is one such synovial-fluid biomarker. However little is known about the performance of the AD-1 assay in the diagnosis of PJI. QUESTIONS/PURPOSES: We sought to (1) determine...

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PMID: 25256621
DOI: 10.1007/s11999-014-3900-7

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