Article
Structural and regulatory mutations in Vibrio parahaemolyticus type III secretion systems display variable effects on virulence.
FEMS microbiology letters - 1 Dec 2014
Calder Thomas, de Souza Santos Marcela, Attah Victoria, Klimko John, Fernandez Jessie, Salomon Dor, Krachler Anne-Marie, Orth Kim
Abstract excerpt
The Gram-negative bacterium, Vibrio parahaemolyticus, is a major cause of seafood-derived food poisoning throughout the world. The pathogenicity of V. parahaemolyticus is attributed to several virulence factors, including two type III secretion systems (T3SS), T3SS1 and T3SS2. Herein, we compare the virulence of V. parahaemolyticus POR strains, which harbor a mutation in the T3SS needle apparatus of either...
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