Article
TssL2 of T6SS2 is required for mobility, biofilm formation, wrinkly phenotype formation, and virulence of Vibrio parahaemolyticus SH112.
Applied microbiology and biotechnology - 17 Dec 2024
Bai Xue-Rui, Liu Peng-Xuan, Wang Wen-Chao, Jin Ying-Hong, Wang Quan, Qi Yu, Zhang Xiao-Yun, Sun Wei-Dong, Fang Wei-Huan, Han Xian-Gan, Jiang Wei
Abstract excerpt
Type VI secretion system 2 (T6SS2) of Vibrio parahaemolyticus is required for cell adhesion and autophagy in macrophages; however, other phenotypes conferred by this T6SS have not been thoroughly investigated. We deleted TssL2, a key component of T6SS2 assembly, to explore the role of the T6SS2 in environmental adaptation and virulence. TssL2 deletion reduced Hcp2 secretion, suggesting that TssL2 played an...
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