Article
The frequency of HLA-B(∗)57:01 and the risk of abacavir hypersensitivity reactions in the majority population of Costa Rica.
Human immunology - 1 Nov 2014
Arrieta-Bolaños Esteban, Madrigal J Alejandro, Marsh Steven G E, Shaw Bronwen E, Salazar-Sánchez Lizbeth
Abstract excerpt
HLA-B(∗)57:01 is a well-known and cost-effective pharmacogenetic marker for abacavir hypersensitivity. As with other HLA alleles, there is widespread variation in its frequency across populations. The Costa Rica Central Valley Population (CCVP) is the major population in this country. The frequency of HLA-B(∗)57:01 in this population has not been described yet. Thus, our aim was to determine the frequency of this...
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