Article
Expression of Heat shock protein 70 (Hsp70-1) in Plasmodium berghei ookinetes and its participation in midgut mosquito infection.
Molecular and biochemical parasitology - 1 Nov 2020
Rodriguez Maria Carmen, Martínez-Barnetche Jesús, Lecona-Valera Alba N, Téllez-Sosa Juan, Argotte-Ramos Rocio S, Alvarado-Delgado Alejandro, Ovilla Marbella T, Saldaña-Navor Vianey, Rodriguez Mario H
Abstract excerpt
The heat shock protein family 70 (Hsp70) comprises chaperone proteins that play major multiple roles in Plasmodium asexual and sexual development. In this study, we analyzed the expression of Hsp70-1 in gametocytes, gametes, zygotes, and its participation in ookinete formation and their transition into oocysts. A monoclonal antibody against recombinant Hsp70-1 revealed its presence in zygotes and micronemes of...
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