Article
The addition of a protease inhibitor increases the risk of infections in patients with hepatitis C-related cirrhosis.
Journal of hepatology - 1 Feb 2015
Londoño Maria-Carlota, Perelló Christie, Cabezas Joaquín, Cañete Nuria, Lens Sabela, Mariño Zoe, Gambato Martina, Rodríguez Raquel, Menéndez Susana, Carrión José A, Crespo Javier, Calleja José Luis, Forns Xavier
Abstract excerpt
BACKGROUND & AIMS: Antiviral therapy with interferon and ribavirin (double therapy) is associated with a significant risk of developing bacterial infections in patients with hepatitis C-related cirrhosis. The addition of telaprevir or boceprevir seems to increase this risk but there are no studies yet to compare the infection rate between both treatments. We aimed to assess rate, type and predictive factors of...
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