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Article

Aberrations of BUBR1 and TP53 gene mutually associated with chromosomal instability in human colorectal cancer.

Anticancer research - 1 Oct 2014

Zhao Yan, Ando Koji, Oki Eiji, Ikawa-Yoshida Ayae, Ida Satoshi, Kimura Yasue, Saeki Hiroshi, Kitao Hiroyuki, Morita Masaru, Maehara Yoshihiko

Abstract excerpt

BACKGROUND/AIM: Defects in mitotic checkpoint and p53-dependent pathways associate with chromosomal instability. In the present study, we investigated the interplay between BUBR1 and p53 and their association with genetic instability in colorectal cancer. PATIENTS AND METHODS: 139 colorectal cases were examined for BUBR1, p53 and genetic instability indicators. BUBR1 expression was evaluated by...

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PMID: 25275037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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