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Article

Age-Related Declines and Disease-Associated Variation in Immune Cell Telomere Length in a Wild Mammal

30 Sept 2014

Abstract excerpt

Immunosenescence, the deterioration of immune system capability with age, may play a key role in mediating age-related declines in whole-organism performance, but the mechanisms that underpin immunosenescence are poorly understood. Biomedical research on humans and laboratory models has documented age and disease related declines in the telomere lengths of leukocytes ('immune cells'), stimulating interest their...

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Share to Immune responses and vaccinations
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Telomeres, Telomerase, and Senescence

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PMID: 25268841
DOI: 10.1371/journal.pone.0108964

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