Article
Age-related variation in immunity in a wild mammal population.
Aging cell - 1 Feb 2012
Nussey Daniel H, Watt Kathryn, Pilkington Jill G, Zamoyska Rose, McNeilly Tom N
Abstract excerpt
Age-related changes in immunity are well documented in humans and laboratory mammals. Using blood samples collected from wild Soay sheep, we show that pronounced differences in T-cell subsets and inflammatory markers amongst age classes are also evident under natural conditions. These shifts parallel those observed in mammals experiencing protected environments. We found progressive declines in the proportion of...
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