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Article

Heterozygote Wdr36-deficient mice do not develop glaucoma.

Experimental eye research - 1 Nov 2014

Gallenberger Martin, Kroeber Markus, März Loreen, Koch Marcus, Fuchshofer Rudolf, Braunger Barbara M, Iwata Takeshi, Tamm Ernst R

Abstract excerpt

There is an ongoing controversy regarding the role of WDR36 sequence variants in the pathogenesis of primary open-angle glaucoma (POAG). WDR36 is a nucleolar protein involved in the maturation of 18S rRNA. The function of WDR36 is essential as homozygous Wdr36-deficient mouse embryos die before reaching the blastocyst stage. Here we provide a detailed analysis of the phenotype of heterozygous Wdr36-deficient...

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Identifiers

PMID: 25261604
DOI: 10.1016/j.exer.2014.09.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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