Article
Association between primary open-angle glaucoma and WDR36 DNA sequence variants in Japanese.
Molecular vision - 9 Oct 2007
Miyazawa Akiko, Fuse Nobuo, Mengkegale MingGe, Ryu Morin, Seimiya Motohiko, Wada Yuko, Nishida Kohji
Abstract excerpt
PURPOSE: To determine whether mutations in the WD repeat domain 36 gene (WDR36) are associated with primary open-angle glaucoma (POAG) in Japanese. Subjects with high tension glaucoma (HTG) and normal tension glaucoma (NTG) were analyzed separately. METHODS: One hundred and thirty-six unrelated Japanese patients with HTG and 103 unrelated patients with NTG were studied. Genomic DNA was extracted from peripheral...
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