Article
Sequence diversity, cytotoxicity and antigenic similarities of the leukotoxin of isolates of Mannheimia species from mastitis in domestic sheep.
Veterinary microbiology - 7 Nov 2014
Omaleki Lida, Browning Glenn F, Barber Stuart R, Allen Joanne L, Srikumaran Subramaniam, Markham Philip F
Abstract excerpt
Species within the genus Mannheimia are among the most important causes of ovine mastitis. Isolates of these species can express leukotoxin A (LktA), a primary virulence factor of these bacteria. To examine the significance of variation in the LktA, the sequences of the lktA genes in a panel of isolates from cases of ovine mastitis were compared. The cross-neutralising capacities of rat antisera raised against...
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